Kevin Neibert.

Background
Kevin obtained his B.Sc. in Biochemistry with a minor in Pharmacology and Therapeutics from McGill in 2008. After a year in the Master’s program in Pharmacology and Therapeutics, he transferred to the Ph.D. program in 2009. In his spare time, he enjoys sports, playing music and computing.

Research highlight
Cerium oxide nanoparticles (nanoceria) have recently become an attractive therapeutic tool, owing to their unique physical and chemical properties . Nanoceria undergo regenerative auto-catalytic superoxide dismutase (SOD) and catalase (CAT) mimetic activity due to the cycling oxidation state of cerium atoms (Ce3+/Ce4+) and presence of oxygen defects in the crystal lattice. The objective of my work is to evaluate the pharmacological potential of nanoceria by investigating its toxicity, therapeutic efficacy and mechanism(s) of action in in-vitro and in-vivo model systems.

Fellowships & awards

  1. Faculty of Medicine Internal Studentship (2011)
  2. Principal's Graduate Fellowship-MD (2009 - 2010)
  3. Barbara Esplin Memorial Prize (2010)
  4. Provost's Graduate Fellowship-MD (2009)

Publications

  1. Wound-Healing with Mechanically Robust and Biodegradable Hydrogel Fibers Loaded with Silver Nanoparticles. Neibert K, Gopishetty V, Grigoryev A, Tokarev I, Al-Hajaj N, Vorstenbosch J, Philip A, Minko S, Maysinger D. Advanced Healthcare Materials [in press, published online July 12, 2012]
  2. Mechanisms of cellular adaptation to quantum dots--the role of glutathione and transcription factor EB. Neibert KD, Maysinger D. Nanotoxicology. 2012 May;6(3):249-62.
  3. Short ligands affect modes of QD uptake and elimination in human cells. Al-Hajaj NA, Moquin A, Neibert KD, Soliman GM, Winnik FM, Maysinger D. ACS Nano. 2011 Jun 28;5(6):4909-18.
  4. Facile Construction of Multifunctional Nanocarriers Using Sequential Click Chemistry for Applications in Biology. Sharma A, Neibert KD, Sharma R, Maysinger D, Kakkar A. Macromolecules 2011;44:521-529.
  5. Probing and preventing quantum dot-induced cytotoxicity with multimodal alpha-lipoic acid in multiple dimensions of the peripheral nervous system. Jain MP, Choi AO, Neibert KD, Maysinger D. Nanomedicine (Lond). 2009 Apr;4(3):277-90.